Aktuelle Publikationen

aktuelle Publikationen

1.

RITA Is Expressed in Trophoblastic Cells and Is Involved in Differentiation Processes of the Placenta.

Wildner JM, Friemel A, Jennewein L, Roth S, Ritter A, Schüttler C, Chen Q, Louwen F, Yuan J, Kreis NN.Cells. 2019 Nov 21;8(12). pii: E1484. doi: 10.3390/cells8121484.PMID:31766533

2.

Subcutaneous and Visceral Adipose-Derived Mesenchymal Stem Cells: Commonality and Diversity.

Ritter A, Friemel A, Roth S, Kreis NN, Hoock SC, Safdar BK, Fischer K, Möllmann C, Solbach C, Louwen F, Yuan J.,Cells. 2019 Oct 21;8(10). pii: E1288. doi: 10.3390/cells8101288.PMID:31640218

3.

The Multifaceted p21 (Cip1/Waf1/CDKN1A) in Cell Differentiation, Migration and Cancer Therapy.

Kreis NN, Louwen F, Yuan J.Cancers (Basel). 2019 Aug 21;11(9). pii: E1220. doi: 10.3390/cancers11091220. Review.PMID:31438587

4.

Restoration of primary cilia in obese adipose-derived mesenchymal stem cells by inhibiting Aurora A or extracellular signal-regulated kinase.

Ritter A, Kreis NN, Roth S, Friemel A, Jennewein L, Eichbaum C, Solbach C, Louwen F, Yuan J.Stem Cell Res Ther. 2019 Aug 14;10(1):255. doi: 10.1186/s13287-019-1373-z.PMID:31412932

5.

RITA modulates cell migration and invasion by affecting focal adhesion dynamics.

Hoock SC, Ritter A, Steinhäuser K, Roth S, Behrends C, Oswald F, Solbach C, Louwen F, Kreis NN, Yuan J.Mol Oncol. 2019 Oct;13(10):2121-2141. doi: 10.1002/1878-0261.12551. Epub 2019 Aug 6.PMID:31353815

6.

Function of p21 (Cip1/Waf1/CDKN1A) in Migration and Invasion of Cancer and Trophoblastic Cells.

Kreis NN, Friemel A, Ritter A, Roth S, Rolle U, Louwen F, Yuan J.Cancers (Basel). 2019 Jul 15;11(7). pii: E989. doi: 10.3390/cancers11070989.PMID:31311187

7.

Potential involvement of RITA in the activation of Aurora A at spindle poles during mitosis.

Kreis NN, Steinhäuser K, Ritter A, Klöble P, Hoock SC, Roth S, Louwen F, Oswald F, Yuan J.Oncogene. 2019 May;38(22):4199-4214. doi: 10.1038/s41388-019-0716-7. Epub 2019 Jan 31.PMID:30705408

8.

Deficient primary cilia in obese adipose-derived mesenchymal stem cells: obesity, a secondary ciliopathy?

Ritter A, Louwen F, Yuan J.Obes Rev. 2018 Oct;19(10):1317-1328. doi: 10.1111/obr.12716. Epub 2018 Jul 17. Review.PMID:30015415

9.

Insight into the development of obesity: functional alterations of adipose-derived mesenchymal stem cells.

Louwen F, Ritter A, Kreis NN, Yuan J.Obes Rev. 2018 Jul;19(7):888-904. doi: 10.1111/obr.12679. Epub 2018 Mar 8. Review.PMID:29521029

10.

Primary Cilia Are Dysfunctional in Obese Adipose-Derived Mesenchymal Stem Cells.

Ritter A, Friemel A, Kreis NN, Hoock SC, Roth S, Kielland-Kaisen U, Brüggmann D, Solbach C, Louwen F, Yuan J.Stem Cell Reports. 2018 Feb 13;10(2):583-599. doi: 10.1016/j.stemcr.2017.12.022. Epub 2018 Jan 27.PMID:29396182

11.Rödel F, Steinhäuser K, Kreis NN, Friemel A, Martin D, Wieland U, Rave-Fränk M, Balermpas P, Fokas E, Louwen F, Rödel C, Yuan J. Prognostic impact of RITA expression in patients with analsqamous cell carcinoma treated with chemoradiotherapy. Radiother Oncol. 2018 Feb;126(2):214-221.  doi: 10.1016/j.radonc.2017.10.028 PMID:29122359

12.Jasmer B, Muschol-Steinmetz C, Kreis NN, Friemel A, Kielland-Kaisen U, Brüggmann D, Jennewein L, Allert R, Solbach C, Yuan J, Louwen F. Involvment of the oncogene B-cell lymphoma 6 in the fusion and differentiation process of trophoblastic cells of the placenta.  Oncotarget.  2017 Aug 24;8(65):108643-108654.  doi: 10.18632/oncotarget.20586. PMID:29312557

 13.Steinhäuser K, Klöble P, Kreis NN, Ritter A, Friemel A, Roth S, Reichel JM, Michaelis J, Rieger MA, Louwen F, Oswald F, Yuan J.  Deficiency of RITA results in multiple mitotic defects by affectingmicrotubule dynamics.   Oncogene.  2017 Apr;36(15):2146-2159. doi: 10.1038/onc.2016.372. Epub 2016 Oct 10.  PMID 27721410

14.Ritter A, Friemel A, Kreis NN, Louwen F, Yuan J.  Impact of Polo-like kinase 1 inhibitors on human adipose tissue-derived mesenchymal stem cells.  Oncotarget. 2016 Dec;7(51):84271-84285. doi: 10.18632/oncotarget.12482.  PMID: 27713178

15.Kreis NN, Friemel A, Zimmer B, Roth S, Rieger MA, Rolle U, Louwen F, Yuan J.Mitoticp21Cip1/CDKN1A is regulated by cyclin-dependent kinase 1 phosphorylation  Oncotarget. 2016 Aug 2;7(31):50215-50228. doi 10.18632/oncotarget.10330.  PMID: 27384476 

16.Ritter A, Kreis NN, Louwen F, Wordeman L, Yuan J.:Molecular insight into the regulation andfunction of MCAK; Crit Rev Biochem Mol Biol. 2015 Jul-Aug;51(4):228-45.45   doi:  10.1008/10409238.2016.1178705. Epub 2016 May 5. Review. PMID. 27146484

17.Muschol-Steinmetz C, Jasmer B, Kreis NN, Steinhäuser K, Ritter A, Rolle U, Yuan J, Louwen F.: B-cell lymphoma 6 promotes Proliferation and survival of trophoblastic cells. Cell Cycle. 2016 Mar 18;15(6):827-39. doi: 10.1080/15384101.2016.1149273. PMID: 27029530

18.Ritter A, Friemel A, Fornoff F, Adjan M, Solbach C, Yuan J, Louwen F.:Characterization of adipose-derived stem cells from subcutaneous and visceral adipose tissues and thei function in breast cancer cells. Oncotarget. 2015 Oct 27;6(33):344475-93. doi: 10.18632/oncotarget.5922. PMID: 2643968

19.Ritter A, Sanhaji M, Friemel A, Roth S, Rolle U, Louwen F, Yuan J.: Funtional Analysis ofphosphorylation of the mitotic centromere-associated kinesin by Aurora B kinase in human tumor cells. Cell Cycle. 2015;14(23):3755-67. doi: 10.1080/15384101.2015.1068481. Epub 2015 Jul 6. PMID: 261482511.

20.Ritter A, Sanhaji M, Steinhäuser K, Roth S, Louwen F, Yuan J.: The activity Regulation of themitotic centromere-associated kinesin by Polo-like kinase 1. Oncotarget. 2015 Mar 30;6(9):6641-55. PMID: 25504441

21.Sanhaji M, Ritter A, Belsham HR, Friel CT, Roth S, Louwen F, Yuan J.: Polo-like kinase 1regulates the stability of the mitotic centromere-associated kinesin in mitosis. Oncotarget. 2014 May 30;5(10):3130-44. PMID 24931513

22.Kreis NN, Louwen F, Zimmer B, Yuan J.: Loss of p21Cip1/CDKN1A renders cancer cells susceptible to Polo-like kinase 1 inhibition. Oncotarget. 2015 Mar 90;6(9):6611-26. PMID: 25483104

23.Kreis NN, Louwen F, Yuan J.:Less understood issues: p21(Cip1) in mitosis and its therapeuticpotential. Oncogene. 2015 Apr 2;34(14):1758-67. doi: 10.10387onc.2014.133. Epub 2014 May 26. Review.PMID: 24858045

24.Louwen F, Muschol-Steinmetz C, Friemel A, Kämpf AK, Töttel E, Reinhard J, Yuan J.: Targeted gene, Analysis: increased B-cell lymphoma 6 in preeclamptic placentas. Hum Pathol. 2014 Jun;45(6):1234-42. doi: 10.1016/j.humpath.2014.02.002. Epub 2014 Feb 20. PMID 24767250

25.Kreis NN, Sanhaji M, Rieger MA, Louwen F, Yuan