Selected Publications

Meis2 is a Pax6 co-factor in neurogenesis and dopaminergic periglomerular fate specification in the adult olfactory bulb.
Agoston Z, Heine P, Brill MS, Grebbin BM, Hau AC, Kallenborn-Gerhardt W, Schramm J, Götz M, Schulte D. 
Development. 2014 Jan;141(1):28-38.

An In Vivo Blood-brain Barrier Permeability Assay in Mice Using Fluorescently Labeled Tracers
Devraj, K., Guérit, S., Macas, J., Reiss, Y.
Journal of visualized experiments. JoVE, 2018; 132 

Alteration of sphingolipid metabolism as a putative mechanism underlying LPS-induced BBB disruption
Vutukuri, R., Brunkhorst, R., Kestner, R.-I., Hansen, L., Bouzas, N.F., Pfeilschifter, J., Devraj, K*., Pfeilschifter, W*.
Journal of Neurochemistry, 2018;  144 (2), pp. 172-185. 

Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy
Hu, J., Dziumbla, S., Lin, J., Bibli, S.-I., Zukunft, S., De Mos, J., Awwad, K., Frömel, T., Jungmann, A., Devraj, K., Cheng, Z., Wang, L., Fauser, S., Eberhart, C.G., Sodhi, A., Hammock, B.D., Liebner, S., Müller, O.J., Glaubitz, C., Hammes, H.-P., Popp, R., Fleming, I.
Nature, 2017; 552 (7684), pp. 248-252. 

Long Noncoding RNA MANTIS Facilitates Endothelial Angiogenic Function
Leisegang, M.S., Fork, C., Josipovic, I., Richter, F.M., Preussner, J., Hu, J., Miller, M.J., Epah, J., Hofmann, P., Günther, S., Moll, F., Valasarajan, C., Heidler, J., Ponomareva, Y., Freiman, T.M., Maegdefessel, L., Plate, K.H., Mittelbronn, M., Uchida, S., Künne, C., Stellos, K., Schermuly, R.T., Weissmann, N., Devraj, K., Wittig, I., Boon, R.A., Dimmeler, S., Pullamsetti, S.S., Looso, M., Miller, F.J., Brandes, R.P.
Circulation, 2017; 136 (1), pp. 65-79. 

Shear stress-regulated miR-27b controls pericyte recruitment by repressing SEMA6A and SEMA6D5.
Demolli, S., Doddaballapur, A., Devraj, K., Stark, K., Manavski, Y., Eckart, A., Zehendner, C.M., Lucas, T., Korff, T., Hecker, M., Massberg, S., Liebner, S., Kaluza, D., Boon, R.A., Dimmeler, S.
Cardiovascular Research, 2017; 113 (6), pp. 681-691. 

BACE-1 is expressed in the blood-brain barrier endothelium and is upregulated in a murine model of Alzheimer's disease
Devraj, K., Poznanovic, S., Spahn, C., Schwall, G., Harter, P.N., Mittelbronn, M., Antoniello, K., Paganetti, P., Muhs, A., Heilemann, M., Hawkins, R.A., Schrattenholz, A., Liebner, S.
Journal of Cerebral Blood Flow and Metabolism, 2016; 36 (7), pp. 1281-1294. 

Angiopoietin-2-induced blood–brain barrier compromise and increased stroke size are rescued by VE-PTP-dependent restoration of Tie2 signaling
Gurnik, S*., Devraj, K*., Macas, J., Yamaji, M., Starke, J., Scholz, A., Sommer, K., Di Tacchio, M., Vutukuri, R., Beck, H., Mittelbronn, M., Foerch, C., Pfeilschifter, W., Liebner, S., Peters, K.G., Plate, K.H., Reiss, Y.
Acta Neuropathologica, 2016; 131 (5), pp. 753-773. 

A novel model for brain iron uptake: Introducing the concept of regulation
Simpson, I.A., Ponnuru, P., Klinger, M.E., Myers, R.L., Devraj, K., Coe, C.L., Lubach, G.R., Carruthers, A., Connor, J.R.
Journal of Cerebral Blood Flow and Metabolism, 2015; 35 (1), pp. 48-57. 

In vitro models of the blood-brain barrier
Czupalla, C.J., Liebner, S., Devraj, K.
Methods in Molecular Biology, 2014; 1135, pp. 415-437. 

GLUT-1 glucose transporters in the blood-brain barrier